Kannabia Sense™: the microbiota Whisperer

Kannabia Sense™ is a neurocosmetic active ingredient that demonstrates the Microbiota-Skin-Brain conneciton in skin care. This 100% natural and plant-based biotech active is a prebiotic ingredient that stimulates the skin microbiota to produce an in-situ postbiotic cocktail that stimulates the synthesis of cutaneous oxytocin. The oxytocin generated in the keratinocytes connects with the sensory neurons and communicates with the brain turning into a well-being response that ends up in a healthier, stronger and prettier appearance. Kannabia Sense™ is a biotech active derived from the stem cells of Cannabis sativa and doesn't contain controversial cannabinoids (THC and CBD free). Kannabia Sense™ is an innovation from Vytrus Biotech awarded at the Innovation Zone Best Ingredient awards of in-cosmetics Global 2020. It's an innovative concept and mechansim based on a plant strategy that efficiently stimulates the skin microbiota to: - Activate brain pleasure areas (oxytocin) - Induces better self-perception and positive emotions - Promotes a healthier and prettier skin Scientifically validated, Kannabia Sense™: - Modulates the oxytocin levels in keratinocytes and sensory neurons - Captures up to 69% of the DPPH, reducing the oxidative stress - Reduces the Kallikrein-5 activity up to a 93% - Inhibits the Hyaluronidase activity up to a 17%, providing a moisturizing activity Clinically tested, Kannabia Sense™: - Increases the skin hydration level by +19% vs placebo - Significantly reduces the frown and marionette lines area and length (mood wrinkles) - Activates the brain pleasures areas (activation profile like oxytocin). Positive brain activation measuring 132 brain regions analyzed by functional Magnetic Resonance Imaging (fMRI) at Hospital de la Fe (Valencia, Spain), approved by an ethical committee - Significantly increases the skin radiance by +18% vs placebo Kannabia Sense™ is an active that demonstrates in vitro and in vivo the neuroendocrine Microbiota-Skin-Brain axis in vivo in the cosmetic sector.

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